Hydrazine hydrate (1:1) → HCID 23362742, compound

HRID 1081559Notes

Reaction equation

HRID 1081559 reaction equation
Cl[C:2](=[N:11][N:12]=[C:13](Cl)[C:14]1[C:19]([F:20])=[CH:18][CH:17]=[CH:16][C:15]=1[F:21])[C:3]1[C:8]([F:9])=[CH:7][CH:6]=[CH:5][C:4]=1[F:10].O.[NH2:24][NH2:25]>O1CCCC1>[F:10][C:4]1[CH:5]=[CH:6][CH:7]=[C:8]([F:9])[C:3]=1[C:2]1[N:24]=[N:25][C:13]([C:14]2[C:19]([F:20])=[CH:18][CH:17]=[CH:16][C:15]=2[F:21])=[N:12][N:11]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 54460818HCID 54460818, compound

Product 1

HCID 23362742HCID 23362742, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

To a solution of 0.9 g of bis[chloro-(2,6-difluorobenzylidene)]hydrazine [prepared in the preceding step b.)] in 18 ml of tetrahydrofuran of 40° C. temperature, 0.59 ml of hydrazine hydrate is dropped over 1 minute. After filtering the precipitate is washed with water and dried to give 0.5 g of desired product as yellow crystals. The melting point is 225.5° C.

Workup

  1. filtrationAfter filtering the precipitate
  2. washis washed with water
  3. customdried

Sources & evidence

ORD record
ord-cf9c58307973414a9c1b040595f9fdab
Source dataset
uspto-grants-1996_12
Patent number
US05587370

Reaction notes

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