Methyl Acrylate → HCID 88359143, compound

HRID 1081994Notes

Reaction equation

HRID 1081994 reaction equation
[C:1](OC)(=O)[CH:2]=[CH2:3].[CH3:7][N:8]([CH2:10][CH2:11][CH2:12][NH2:13])[CH3:9].[CH3:14][O-:15].[Na+]>>[CH3:7][N:8]([CH2:10][CH2:11][CH2:12][NH:13][C:14](=[O:15])[CH:12]([NH:13][CH2:1][CH:2]([N:8]([CH3:9])[CH3:7])[CH3:3])[CH3:11])[CH3:9]

Participants

4

Reactant 3

HCID 7294Methyl AcrylateHCID 7993N,N-Dimethyl-1,3-propanediamineHCID 10942334Sodium Methoxide

Product 1

HCID 88359143HCID 88359143, compound

Procedure

To 4 moles of methyl acrylate were added 8.8 moles of dimethylaminopropylamine and the mixture was subjected to an addition reaction in the same manner as in Comparative Example 2. Then sodium methoxide was added thereto to conduct the amidation reaction. After completion of the reaction, the low-boiling-point substances were removed by distillation to give a crude N-dimethylaminopropyl-beta-dimethylaminopropylaminopropionamide. This contained about 13% of high-boiling-point impurities.

Workup

  1. additionthe mixture was subjected to an addition reaction in the same manner as in Comparative Example 2
  2. customthe amidation reaction
  3. customAfter completion of the reaction
  4. customthe low-boiling-point substances were removed by distillation

Sources & evidence

ORD record
ord-fe049d75cd804bf6985d476a6ecd1b09
Source dataset
uspto-grants-1996_12
Patent number
US05587515

Reaction notes

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