Ethyl Acetate → 2-Methylbenzenesulfonic acid

HRID 1084301Notes

Reaction equation

HRID 1084301 reaction equation
O.[C:2]1(C)[CH:7]=[CH:6][C:5]([S:8]([OH:11])(=[O:10])=[O:9])=[CH:4][CH:3]=1.[CH2:13](OC(=O)C)C>>[C:4]1([CH3:13])[C:5]([S:8]([OH:11])(=[O:9])=[O:10])=[CH:6][CH:7]=[CH:2][CH:3]=1

Participants

3

Reactant 2

HCID 8857Ethyl AcetateHCID 521998p-Toluenesulfonic acid monohydrate

Product 1

HCID 69252-Methylbenzenesulfonic acid

Procedure

The present invention is to provide a compound (I') which comprises (d) reacting the produced compound (I) with p-toluenesulfonic acid monohydrate in the presence of ethylacetate to produce toluenesulfonic acid 1,1-dioxppenicillanoyl oxymethyl D-6-[(α-methyleneamino) phenylacetamido]-penicillanate (I') in accordance with the present invention.

Workup

  1. customto provide a compound (I') which

Sources & evidence

ORD record
ord-3f74d05cecf54d7584d1d6d9975e9588
Source dataset
uspto-grants-1991_04
Patent number
US05004738

Reaction notes

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