Sodium Bicarbonate → HCID 67920204, compound

HRID 1084807Notes

Reaction equation

HRID 1084807 reaction equation
[CH2:1]([P:4]([CH3:9])(=[O:8])[O:5][CH2:6][CH3:7])[CH:2]=[CH2:3].C(=O)(O)[O-].[Na+].[Br:15][C:16](Br)=[N:17][OH:18]>C(OCC)(=O)C.O>[Br:15][C:16]1[CH2:3][CH:2]([CH2:1][P:4]([CH3:9])(=[O:8])[O:5][CH2:6][CH3:7])[O:18][N:17]=1

Participants

6

Reactant 3

HCID 516892Sodium BicarbonateHCID 27632191-bromo-N-hydroxymethanecarbonimidoyl bromideHCID 20062392Ethyl methyl(prop-2-en-1-yl)phosphinate

Product 1

HCID 67920204HCID 67920204, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 8857Ethyl AcetateSolvent3×

Procedure

20 g (0.135 mol) of ethyl allyl(P-methyl)phosphinate are dissolved in 570 ml of ethyl acetate, 49.7 g (0.6 mol) of sodium bicarbonate in 115 ml of water are added and, while stirring vigorously, a solution of 40.6 g (0.2 mol) of dibromoformaldoxime in 115 ml of ethyl acetate is slowly added dropwise. The product is isolated in the form of an oil, 15 g from the ethyl acetate phase, and a further 19 g from the aqueous phase by extraction with dichloromethane at pH 2.

Workup

  1. extractiona further 19 g from the aqueous phase by extraction with dichloromethane at pH 2

Sources & evidence

ORD record
ord-426bdf1072954337bd2c64c1f4a87bc0
Source dataset
uspto-grants-1991_04
Patent number
US05006515

Reaction notes

Loading…