HCID 14835239, compound → HCID 14835240, compound

HRID 1084905Notes

Reaction equation

HRID 1084905 reaction equation
[CH3:1][N:2]([CH:15]1[CH2:23][C:22]2[C:17](=[CH:18][CH:19]=[C:20]([N+:24]([O-])=O)[CH:21]=2)[CH2:16]1)[CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[CH:8][CH:7]=1>C(OCC)(=O)C.[Pd]>[NH2:24][C:20]1[CH:21]=[C:22]2[C:17](=[CH:18][CH:19]=1)[CH2:16][CH:15]([N:2]([CH2:3][CH2:4][O:5][C:6]1[CH:7]=[CH:8][C:9]([NH2:12])=[CH:10][CH:11]=1)[CH3:1])[CH2:23]2

Participants

4

Reactant 1

HCID 14835239HCID 14835239, compound

Product 1

HCID 14835240HCID 14835240, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

A solution of 2-[N-methyl-N-(2-{4-nitrophenoxy}ethyl)amino]-5-nitroindane (0.3 g) in ethyl acetate (30 ml) containing 5% Pd/C (0.03 g) was stirred under a hydrogen atmosphere [206.8 kPa (30 p.s.i.)] for 2 hours at room temperature. The catalyst was then removed by filtration and the filtrate evaporated in vacuo to afford the title compound as a gum, yield 0.25 g, which was used directly without further purification.

Workup

  1. customThe catalyst was then removed by filtration
  2. customthe filtrate evaporated in vacuo

Sources & evidence

ORD record
ord-ecd09c617621499ea78c4f1a2dc52d08
Source dataset
uspto-grants-1991_04
Patent number
US05006561

Reaction notes

Loading…