Methanesulfonic Acid → HCID 13983512, compound

HRID 1084928Notes

Reaction equation

HRID 1084928 reaction equation
[C:1]1([CH2:7][N:8]2[CH2:12][CH2:11][CH2:10][CH:9]2[CH2:13][NH:14][C:15]([C:17]2[C:25]3[O:24][CH:23]([CH3:26])[CH2:22][C:21]=3[CH:20]=[C:19]([S:27]([CH2:30][CH:31]3[CH2:33][CH2:32]3)(=[O:29])=[O:28])[CH:18]=2)=[O:16])[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]=1.[CH3:34][S:35]([OH:38])(=[O:37])=[O:36]>C(OCC)(=O)C>[CH3:34][S:35]([OH:38])(=[O:37])=[O:36].[C:1]1([CH2:7][N:8]2[CH2:12][CH2:11][CH2:10][CH:9]2[CH2:13][NH:14][C:15]([C:17]2[C:25]3[O:24][CH:23]([CH3:26])[CH2:22][C:21]=3[CH:20]=[C:19]([S:27]([CH2:30][CH:31]3[CH2:32][CH2:33]3)(=[O:28])=[O:29])[CH:18]=2)=[O:16])[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]=1

Participants

4

Reactant 2

HCID 6395Methanesulfonic AcidHCID 13983511HCID 13983511, compound

Product 1

HCID 13983512HCID 13983512, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

141 g of N-(1-cyclohexenylmethyl-2-pyrrolidinyl-methyl)-5-cyclopropylmethylsulphonyl-2-methyl-2,3-dihydrobenzofuran-7-carboxamide were dissolved in 340 ml of ethyl acetate and 29 g of methanesulphonic acid were then added.

Sources & evidence

ORD record
ord-4020b6b03cbf4c2ba76aef0a3d910636
Source dataset
uspto-grants-1991_04
Patent number
US05006570

Reaction notes

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