Ammonium Acetate → HCID 14745925, compound

HRID 1085241Notes

Reaction equation

HRID 1085241 reaction equation
[Cl:1]/[C:2](/[C:12]([O:14][CH2:15][CH:16]([CH3:18])[CH3:17])=[O:13])=[C:3](\Cl)/[C:4]([O:6][CH2:7][CH:8]([CH3:10])[CH3:9])=[O:5].C([O-])(=O)C.[NH4+:23]>CN(C)C=O>[NH2:23]/[C:3](/[C:4]([O:6][CH2:7][CH:8]([CH3:10])[CH3:9])=[O:5])=[C:2](\[Cl:1])/[C:12]([O:14][CH2:15][CH:16]([CH3:18])[CH3:17])=[O:13]

Participants

4

Reactant 2

HCID 517165Ammonium AcetateHCID 19902722HCID 19902722, compound

Product 1

HCID 14745925HCID 14745925, compoundYield 80.3%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

29.7 g (0.1 mol) of diisobutyl dichloromaleate, 19.27 g (0.25 mol) of ammonium acetate and 40 ml of dimethylformamide were reacted under the same conditions as described in Example 1. A reddish oil was obtained which crystallized on trituration. After the crystal slurry had been washed with hexane, 22.3 g (80%) of diisobutyl aminochloromaleate were obtained as cubic crystals (m.p. 80° C.-81° C.).

Workup

  1. customA reddish oil was obtained which
  2. customcrystallized on trituration
  3. washAfter the crystal slurry had been washed with hexane

Sources & evidence

ORD record
ord-e715ba01e2ce4ede8b1b1635a70786ec
Source dataset
uspto-grants-1991_04
Patent number
US05008392

Reaction notes

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