Chloride → 1-(6-Bromo-pyridin-2-ylmethyl)-3-(5-bromo-pyrimidine-2-carbonyl)-1H-quinolin-4-one

HRID 108561Notes

Reaction equation

HRID 108561 reaction equation
[Br:26][c:27]1[cH:28][n:29][c:30]([I:33])[n:31][cH:32]1.[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH3:1][O:2][N:3]([C:4](=[O:5])[c:6]1[cH:7][n:8]([CH2:17][c:18]2[n:19][c:20]([Br:24])[cH:21][cH:22][cH:23]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][c:14]2[c:15]1=[O:16])[CH3:25].[CH:35]([Mg+:36])([CH3:37])[CH3:38].[Cl-:34]>>[C:4](=[O:5])([c:6]1[cH:7][n:8]([CH2:17][c:18]2[n:19][c:20]([Br:24])[cH:21][cH:22][cH:23]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][c:14]2[c:15]1=[O:16])[c:30]1[n:29][cH:28][c:27]([Br:26])[cH:32][n:31]1

Participants

6

Reactant 5

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 70066515-Bromo-2-iodopyrimidineHCID 577545321-(6-Bromo-pyridin-2-ylmethyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid methoxy-methyl-amideHCID 178461726HCID 178461726, compound

Product 1

HCID 577547211-(6-Bromo-pyridin-2-ylmethyl)-3-(5-bromo-pyrimidine-2-carbonyl)-1H-quinolin-4-one

Sources & evidence

ORD record
ord-5ec880155b6e486f80c8acbf61ccf476
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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