Methyl 3-iodobenzoate → HCID 19768519, compound

HRID 1085849Notes

Reaction equation

HRID 1085849 reaction equation
[I:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][CH:11]=1)[C:5]([O:7][CH3:8])=O.COC1C=CC(P2(SP(C3C=CC(OC)=CC=3)(=S)S2)=[S:21])=CC=1>C1(C)C(C)=CC=CC=1>[I:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][CH:11]=1)[C:5]([O:7][CH3:8])=[S:21]

Participants

4

Reactant 2

HCID 69258Methyl 3-iodobenzoateHCID 87949Lawesson's reagent

Product 1

HCID 19768519HCID 19768519, compoundYield 84.5%

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

52.5 g (0.2 mol) of methyl 3-iodobenzoate were heated to reflux for 18 hours with 81 g (0.2 mol) of Lawesson reagent in 330 ml of xylene. By working-up in an analogous manner to that described in Example 1(B) there were obtained 47 g (84.4%) of O-methyl 3-iodothiobenzoate as a yellow evil-smelling oil which was used without further purification.

Sources & evidence

ORD record
ord-363fa08194634b6280b5403a107ec2ca
Source dataset
uspto-grants-1991_04
Patent number
US05011849

Reaction notes

Loading…