Benzoylhydrazine → HCID 53876524, compound

HRID 1085941Notes

Reaction equation

HRID 1085941 reaction equation
[C:1]([C:5]1[CH:6]=[N:7][CH:8]=[CH:9][CH:10]=1)(=O)[CH2:2][CH3:3].[C:11]([NH:19][NH2:20])(=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>C(O)C>[N:7]1[CH:8]=[CH:9][CH:10]=[C:5]([C:1](=[N:20][NH:19][C:11](=[O:18])[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:2][CH3:3])[CH:6]=1

Participants

4

Reactant 2

HCID 11955BenzoylhydrazineHCID 740741-(3-Pyridyl)propan-1-one

Product 1

HCID 53876524HCID 53876524, compoundYield 80.4%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 6.76 gm (0.05 mole) of 3-propionylpyridine, 6.81 gm (0.05 mole) of benzhydrazide and 100 ml of absolute ethanol is refluxed 8.5 hr. The hot solution is filtered. The filtrate is cooled to room temperature and then chilled. The crystals that separate are collected and dried to yield 10.18 gm (80%) of the title compound having a melting point of 169.4° C.

Workup

  1. temperatureis refluxed 8.5 hr
  2. filtrationThe hot solution is filtered
  3. temperaturechilled
  4. customThe crystals that separate
  5. customare collected
  6. customdried

Sources & evidence

ORD record
ord-90034a4423a94f56a8dbc194bdba5b32
Source dataset
uspto-grants-1991_04
Patent number
US05011932

Reaction notes

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