反应详情

To a suspension of 0.24 g of sodium hydride in 40 ml of N,N-dimethylformamide was added dropwise a solution of 1.27 g of 2-cyanoiminothiazolidine in 10 ml of N,N-dimethylformamide, and the mixture was stirred at room temperature for 30 minutes. After stirring, 1.27 g of benzyl chloride was added, and the mixture was stirred at temperature for 2 hours. After the reaction, the solvent was evaporated under reduced pressure, water was added to the residue, and the resulting crystals were then collected by filtration to give 1.84 g of 3-benzyl-2-cyanoiminothiazolidine.

1. stirringAfter stirring
2. stirringthe mixture was stirred at temperature for 2 hours
3. customAfter the reaction
4. customthe solvent was evaporated under reduced pressure, water
5. additionwas added to the residue
6. filtrationthe resulting crystals were then collected by filtration