Methylamine → HCID 14677075, compound

HRID 1086390Notes

Reaction equation

HRID 1086390 reaction equation
[CH3:1][NH2:2].[CH2:3]([S:5]([CH2:8][CH2:9]Cl)(=[O:7])=[O:6])[CH3:4]>C1(C)C=CC=CC=1>[CH3:1][NH:2][CH2:9][CH2:8][S:5]([CH2:3][CH3:4])(=[O:7])=[O:6]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 101406Ethane, 1-chloro-2-(ethylsulfonyl)-

Product 1

HCID 14677075HCID 14677075, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Conditions

Temperature
50 °C

Procedure

Gaseous methylamine is passed to saturation (about 30 min) into a solution of 15.7 g of chloroethyl ethyl sulfone in 100 ml of toluene at an internal temperature of 50° C. The mixture is stirred at 50° C. for 3 h, the precipitate is filtered off with suction, and the filtrate is concentrated in a rotary evaporator. The remaining yellow mobile liquid (12.3 g) is reacted without further purification.

Workup

  1. filtrationthe precipitate is filtered off with suction
  2. concentrationthe filtrate is concentrated in a rotary evaporator
  3. customThe remaining yellow mobile liquid (12.3 g) is reacted without further purification

Sources & evidence

ORD record
ord-7ed1fbeb69b444819da3f0b8709dc87d
Source dataset
uspto-grants-1991_07
Patent number
US05030270

Reaction notes

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