反应详情

温度

125 °C

18.32 g (100 mmoles) of undecyl cyanide, 8.5 ml (127 mmole) of ethylenediamine and 0.5 ml of carbon disulfide were mixed and heated in an oil bath at 125° C. for 24 hours. The reaction mixture was cooled, treated with dilute hydrochloric acid and treated with charcoal. The light yellow filtrate was basified and extracted with ethyl acetate, the organic extracts dried over magnesium sulfate and concentrated. The residue was Kugelrohr distilled and then recrystallized from toluene. Yield 13.7 g (61.1%), m.p. 82° C.

1. temperatureThe reaction mixture was cooled
2. extractionextracted with ethyl acetate
3. dry with materialthe organic extracts dried over magnesium sulfate
4. concentrationconcentrated
5. distillationdistilled
6. customrecrystallized from toluene