Triethylamine → N-methyl-N-[(2-methyl-6-pyridinyl)methyl]-2-propenamide

HRID 1086461Notes

Reaction equation

HRID 1086461 reaction equation
[CH3:1][C:2]1[N:7]=[C:6]([CH2:8]CN)[CH:5]=[CH:4][CH:3]=1.[C:11](Cl)(=[O:14])[CH:12]=[CH2:13].[CH2:16]([N:18](CC)CC)C>C(Cl)Cl>[CH3:16][N:18]([CH2:8][C:6]1[N:7]=[C:2]([CH3:1])[CH:3]=[CH:4][CH:5]=1)[C:11](=[O:14])[CH:12]=[CH2:13]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 13140Acryloyl chlorideHCID 15141652-(6-Methylpyridin-2-yl)ethan-1-amine

Product 1

HCID 19826106N-methyl-N-[(2-methyl-6-pyridinyl)methyl]-2-propenamide

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title compound was prepared according to the method of Example 6 from 6-methyl-2-picolylmethylamine (4.27 g, 0.035 mole), acryloyl chloride (3.15 g, 0.035 mole) and triethylamine (21 ml) in methylene chloride. Analysis calc. for C11H14N2O(190.24): Calc.: C, 69.44; H, 7.42; N, 14.72. Found: C, 69.41; H, 7.53; N, 14.68.

Sources & evidence

ORD record
ord-3261731c980047bf80a0c6dfc02c0a2c
Source dataset
uspto-grants-1991_07
Patent number
US05030642

Reaction notes

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