Acryloyl chloride → HCID 13822941, compound

HRID 1086462Notes

Reaction equation

HRID 1086462 reaction equation
[CH3:1][NH:2][CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][N:8]=[CH:7][CH:6]=1.[C:11](Cl)(=[O:14])[CH:12]=[CH2:13]>C(N(CC)CC)C>[CH3:1][N:2]([CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][N:8]=[CH:7][CH:6]=1)[C:11](=[O:14])[CH:12]=[CH2:13]

Participants

4

Reactant 2

HCID 13140Acryloyl chlorideHCID 143276Methyl[2-(pyridin-4-yl)ethyl]amine

Product 1

HCID 13822941HCID 13822941, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

The title compound was prepared according to the method of Example 3 from 4-[β-(methylamino)ethyl]pyridine (4.76 g, 0.035 mole), acryloyl chloride (3.15 g, 0.035 mole) and triethylamine (21 ml) to yield 3.4 g of product, m.p. ca. 129°-132° C. Analysis calc. for C11H14N2O(190.24): Calc.: C, 69.45; H, 7.42; N, 14.72. Found: C, 69.79; H, 7.62; N, 14.20.

Sources & evidence

ORD record
ord-086226f0b36941319209120b794a7985
Source dataset
uspto-grants-1991_07
Patent number
US05030642

Reaction notes

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