HCID 13822937, compound → 3-[(2'-hydroxy[1,1':3',1"-terphenyl]-5'-yl)-thio]-N-methyl-N-[2-(2-pyridin-yl)ethyl]propanamide

HRID 1086467Notes

Reaction equation

HRID 1086467 reaction equation
[SH:1][C:2]1[CH:3]=[C:4]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[C:5]([OH:14])=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:7]=1.[CH3:21][N:22]([CH2:27][CH2:28][C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][N:30]=1)[C:23](=[O:26])[CH:24]=[CH2:25]>C(N(CC)CC)C>[OH:14][C:5]1[C:6]([C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=2)=[CH:7][C:2]([S:1][CH2:25][CH2:24][C:23]([N:22]([CH3:21])[CH2:27][CH2:28][C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][N:30]=2)=[O:26])=[CH:3][C:4]=1[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

Participants

4

Reactant 2

HCID 13822937HCID 13822937, compoundHCID 149891685'-Mercapto[1,1':3',1"-terphenyl]-2'-ol

Product 1

HCID 198261093-[(2'-hydroxy[1,1':3',1"-terphenyl]-5'-yl)-thio]-N-methyl-N-[2-(2-pyridin-yl)ethyl]propanamide

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

The title compound was prepared according to the method of Example 4 from the thiol of Example 16(2.78 g, 0.01 mole), N-methyl-N-[2-(2-pyridinyl)ethyl]-2-propenamide (1.90 g, 0.01 mold) and triethylamine (1.2 ml). Analysis calc. for C29H28O2N2S (468.54): Calc.: C, 74.32; H, 6.02; N, 5.98. Found: C, 73.93; H, 6.04; N, 6.16.

Sources & evidence

ORD record
ord-161c26c98a5143b090297f1486396030
Source dataset
uspto-grants-1991_07
Patent number
US05030642

Reaction notes

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