Pyridine → N-[4-[(3-Bromophenyl)amino]-3-cyano-6-quinolinyl]-4-(N-ethylpiperazino)-2-butynamide
Reaction equation
[CH2:9]([CH3:10])[N:11]1[CH2:12][CH2:13][N:14]([CH2:17][C:18]#[C:19][C:20](=[O:21])[OH:22])[CH2:15][CH2:16]1.[CH3:23][N:24]1[CH2:25][CH2:26][O:27][CH2:28][CH2:29]1.[Cl:1][C:2]([O:3][CH2:4][CH:5]([CH3:6])[CH3:7])=[O:8].[NH2:30][c:31]1[cH:32][c:33]2[c:34]([NH:43][c:44]3[cH:45][c:46]([Br:50])[cH:47][cH:48][cH:49]3)[c:35]([C:41]#[N:42])[cH:36][n:37][c:38]2[cH:39][cH:40]1.[cH:51]1[cH:52][cH:53][n:54][cH:55][cH:56]1>>[CH2:9]([CH3:10])[N:11]1[CH2:12][CH2:13][N:14]([CH2:17][C:18]#[C:19][C:20](=[O:22])[NH:30][c:31]2[cH:32][c:33]3[c:34]([NH:43][c:44]4[cH:45][c:46]([Br:50])[cH:47][cH:48][cH:49]4)[c:35]([C:41]#[N:42])[cH:36][n:37][c:38]3[cH:39][cH:40]2)[CH2:15][CH2:16]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d840a925078842b0909f822eb5232279
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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