反应详情

The mixture constituted by 0.24 mole (57 g) 6-benzyloxy-1-methylindole, 5.7 g 10% palladium-on-charcoal, 114 ml cyclohexane and 170 ml 96° ethanol is heated for 30 minutes under reflux. It is filtered hot in order to remove the catalyst. After evaporation of the filtrate under vacuum, an oil is obtained which, when dissolved in isopropyl ether, leads after evaporation to dryness to the desired product. It melts at 74° C.

1. temperatureis heated for 30 minutes
2. temperatureunder reflux
3. filtrationIt is filtered hot in order
4. customto remove the catalyst
5. customAfter evaporation of the filtrate under vacuum
6. customan oil is obtained which, when
7. customafter evaporation to dryness to the desired product