m-Chloroperbenzoic acid → 4-[2-[Ethyl[3-(propylsulfinyl)propyl]amino]-1-hydroxyethyl]-benzonitrile

HRID 1087115Notes

Reaction equation

HRID 1087115 reaction equation
[CH2:1]([N:3]([CH2:15][CH2:16][CH2:17][S:18][CH2:19][CH2:20][CH3:21])[CH2:4][CH:5]([C:7]1[CH:14]=[CH:13][C:10]([C:11]#[N:12])=[CH:9][CH:8]=1)[OH:6])[CH3:2].ClC1C=CC=C(C(OO)=[O:30])C=1>>[CH2:1]([N:3]([CH2:15][CH2:16][CH2:17][S:18]([CH2:19][CH2:20][CH3:21])=[O:30])[CH2:4][CH:5]([C:7]1[CH:14]=[CH:13][C:10]([C:11]#[N:12])=[CH:9][CH:8]=1)[OH:6])[CH3:2]

Participants

3

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 151588164-[2-[Ethyl[3-(propylthio)propyl]amino]-1-hydroxyethyl]-benzonitrile

Product 1

HCID 151588174-[2-[Ethyl[3-(propylsulfinyl)propyl]amino]-1-hydroxyethyl]-benzonitrileYield 73.9%

Procedure

0.9 g of 4-[2-[ethyl[3-(propylthio)propyl]amino]-1-hydroxyethyl]-benzonitrile was oxidized with 0.7 g of m-chloroperbenzoic acid in analogy with example 2. Yield: 0.7 g of the title compound.

Sources & evidence

ORD record
ord-1ba397ba134e4517b1268dba87bc6762
Source dataset
uspto-grants-1991_07
Patent number
US05034411

Reaction notes

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