反应详情

5.0 g of 4-[4-[(2-hydroxyethyl)amino]butyl]benzonitrile and 4.9 g of 1-bromo-3-(propylthio)propane were dissolved in 50 ml of isopropanol. 6.3 g of potassium-carbonate was added and the mixture was refluxed over night and thereafter filtrated and evaporated. The oily residue was purified by column chromotography. Yield: 4.3 g of the title compound.

1. temperaturethe mixture was refluxed over night
2. filtrationfiltrated
3. customevaporated
4. customThe oily residue was purified by column chromotography