Diazomethane → HCID 15661028, compound

HRID 1087388Notes

Reaction equation

HRID 1087388 reaction equation
[C:1]([C:4]1[CH:21]=[CH:20][C:7]2[S:8][C:9]3[CH:16]=[C:15]([C:17]([OH:19])=[O:18])[CH:14]=[CH:13][C:10]=3[CH2:11][CH2:12][C:6]=2[CH:5]=1)(=[O:3])[CH3:2].[N+](=[CH2:24])=[N-]>C(OCC)(=O)C.CCOCC>[C:1]([C:4]1[CH:21]=[CH:20][C:7]2[S:8][C:9]3[CH:16]=[C:15]([C:17]([O:19][CH3:24])=[O:18])[CH:14]=[CH:13][C:10]=3[CH2:11][CH2:12][C:6]=2[CH:5]=1)(=[O:3])[CH3:2]

Participants

5

Reactant 2

HCID 9550DiazomethaneHCID 13151869HCID 13151869, compound

Product 1

HCID 15661028HCID 15661028, compound

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 8857Ethyl AcetateSolvent

Procedure

To a solution of 2-acetyl-10,11-dihydro-dibenzo[b,f]thiepin-7-carboxylic acid (U.S. Pat. No. 4,536,507 (1985)) (600 mg, 2.01 mmol) in ethyl acetate (10 mL), was added dropwise a solution of diazomethane in ether until the yellow coloration persisted. Evaporation of the solvent gave the crude title compound as a solid which was used as such.

Workup

  1. customEvaporation of the solvent

Sources & evidence

ORD record
ord-33b3b866504b46938a7cba5eb4609c1e
Source dataset
uspto-grants-1991_07
Patent number
US05036067

Reaction notes

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