Octylamine → 1-(2-Hydroxyethyl)-3-octylimidazolidin-2-one

HRID 1087758Notes

Reaction equation

HRID 1087758 reaction equation
Cl[CH2:2][CH2:3][N:4]1[CH2:8][CH2:7][O:6][C:5]1=[O:9].[CH2:10]([NH2:18])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17]>C(OCC)(=O)C>[OH:6][CH2:7][CH2:8][N:4]1[CH2:3][CH2:2][N:18]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[C:5]1=[O:9]

Participants

4

Reactant 2

HCID 8143OctylamineHCID 756333-(2-Chloroethyl)-1,3-oxazolidin-2-one

Product 1

HCID 148362191-(2-Hydroxyethyl)-3-octylimidazolidin-2-oneYield 83%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

7.1 g of 3-(2-chloroethyl)oxazolidin-2-one was treated with 12.271 g of octyl amine. The reaction mixture was stirred overnight, diluted with ethyl acetate and washed with water and brine. The organic solution was dried and concentrated to give 9.55 g (83%) of product.

Workup

  1. washwashed with water and brine
  2. customThe organic solution was dried
  3. concentrationconcentrated

Sources & evidence

ORD record
ord-2516ec45db7847b0ac73ae7bc7c74848
Source dataset
uspto-grants-1990_10
Patent number
US04960771

Reaction notes

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