Hydrogen Bromide → HCID 22163881, compound

HRID 1087774Notes

Reaction equation

HRID 1087774 reaction equation
[Br:1]Br.[C:3]([C:6]1[CH:14]=[CH:13][C:9]2[N:10]=[CH:11][NH:12][C:8]=2[CH:7]=1)(=[O:5])[CH3:4].[BrH:15]>C(O)(=O)C>[BrH:1].[Br:15][CH2:4][C:3]([C:6]1[CH:14]=[CH:13][C:9]2[N:10]=[CH:11][NH:12][C:8]=2[CH:7]=1)=[O:5]

Participants

5

Reactant 3

HCID 260Hydrogen BromideHCID 24408BromineHCID 122629041-(1H-Benzimidazol-6-yl)ethan-1-one

Product 1

HCID 22163881HCID 22163881, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent2×

Conditions

Temperature
40 °C

Procedure

1.21 g (7.6 mmol) of bromine in 5 ml of glacial acetic acid are added to a solution of 1.2 g (7.5 mmol) of 5-acetylbenzimidazole and 1.35 g of 48% strength aqueous HBr (=8 mmol of HB) in 15 ml of glacial acetic acid at room temperature. The mixture is stirred at 40° C. for 30 minutes and cooled and the product which has precipitated out is filtered off.

Workup

  1. temperaturecooled
  2. customthe product which has precipitated out
  3. filtrationis filtered off

Sources & evidence

ORD record
ord-b1793726a0e646c58847c84ea25c9226
Source dataset
uspto-grants-1990_10
Patent number
US04960783

Reaction notes

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