Pyridine → HCID 86744248, compound

HRID 1087795Notes

Reaction equation

HRID 1087795 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[N:9]1[CH:13]=[CH:12][C:11]([C:14](=O)[CH3:15])=[CH:10]1.Cl.[NH2:18][OH:19].N1C=CC=CC=1>CO>[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[N:9]1[CH:13]=[CH:12][C:11]([C:14](=[N:18][OH:19])[CH3:15])=[CH:10]1

Participants

5

Reactant 3

HCID 1049PyridineHCID 443297Hydroxyamine hydrochlorideHCID 22163909HCID 22163909, compound

Product 1

HCID 86744248HCID 86744248, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of 1-(2,6-dimethylphenyl)-3-acetyl-1H-pyrrole (20.0 g), hydroxylamine hydrochloride (25.0 g), pyridine (130 ml) in 100 ml of methanol is heated under reflux for 20 hours. Workup in the usual manner yields 1-(2,6-dimethylphenyl)-3-acetyl-1H-pyrrole oxime.

Workup

  1. temperatureis heated
  2. temperatureunder reflux for 20 hours

Sources & evidence

ORD record
ord-a5951e8838f7418cb50abf68382dd20b
Source dataset
uspto-grants-1990_10
Patent number
US04960787

Reaction notes

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