Dichloroacetyl chloride → HCID 15713153, compound

HRID 1089326Notes

Reaction equation

HRID 1089326 reaction equation
[CH3:1][C:2]1([CH3:12])[NH:6][CH2:5][CH:4]([CH2:7][O:8][CH:9]([CH3:11])[CH3:10])[O:3]1.[Cl:13][CH:14]([Cl:18])[C:15](Cl)=[O:16].C(N(CC)CC)C>C1C=CC=CC=1>[CH3:1][C:2]1([CH3:12])[N:6]([C:15](=[O:16])[CH:14]([Cl:18])[Cl:13])[CH2:5][CH:4]([CH2:7][O:8][CH:9]([CH3:10])[CH3:11])[O:3]1

Participants

5

Reactant 3

HCID 6593Dichloroacetyl chlorideHCID 8471TriethylamineHCID 15713151HCID 15713151, compound

Product 1

HCID 15713153HCID 15713153, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

In a similar manner as Example I, 27.7 milliliters of 25 percent w/v, 2,2-dimethyl-5-isopropoxymethyl oxazolidine solution in 50 milliliters of benzene and 4.9 grams of dichloroacetyl chloride was added 4.1 grams of triethylamine. After the appropriate work up procedure, there was obtained a yield of 8.9 grams, nD30 1.4564. Analytical data supports the structure.

Workup

  1. customAfter the appropriate work up procedure, there was obtained a yield of 8.9 grams

Sources & evidence

ORD record
ord-5baf44fb88254009bc0acf6883d38697
Source dataset
uspto-grants-1990_10
Patent number
US04965368

Reaction notes

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