Triethylamine → HCID 22160874, compound

HRID 1089330Notes

Reaction equation

HRID 1089330 reaction equation
[CH3:1][C:2]1([CH3:11])[NH:6][CH2:5][CH:4]([CH2:7][S:8][CH2:9][CH3:10])[O:3]1.[CH2:12]([N:14]([CH2:17]C)CC)[CH3:13].C(C1C(Cl)=C(C([O-])=O)[S:24]C=1)C.CC1(C)N(C(=O)CCl)CC(CSCC)O1>C1C=CC=CC=1>[CH3:1][C:2]1([CH3:11])[N:6]([C:17](=[S:24])[NH:14][CH2:12][CH3:13])[CH2:5][CH:4]([CH2:7][S:8][CH2:9][CH3:10])[O:3]1

Participants

6

Reactant 4

HCID 8471TriethylamineHCID 15713182HCID 15713182, compound2×HCID 22160872HCID 22160872, compoundHCID 86744313HCID 86744313, compound

Product 1

HCID 22160874HCID 22160874, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

To 19.3 milliliters of 25 percent w/v, 2,2-dimethyl-5-ethylthiomethyl oxazolidine solution in 25 milliliters of benzene was added 2.9 grams of triethylamine and 3.4 grams of ethylchlorothiolformate as in the procedure for (a) supra. Work-up was similar to (a). There was obtained a yield of 7.1 grams of the title compound, nD30 1.4940. Infrared data supports the structure.

Sources & evidence

ORD record
ord-ba5bf78d942c4956ba801f625aee4be8
Source dataset
uspto-grants-1990_10
Patent number
US04965368

Reaction notes

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