反应详情

To ethyl acetate (1 L) add 4-[(4-methylphenyl)sulfonyl]-9-nitro-3,4,5,6-tetrahydro-2H-1,7,4-benzodioxazonine (7.5 g, 20 mmol) and Pd(OH)2 on carbon (1.0 g). Place the reaction mixture on a Parr hydrogenator and shake at 50 psi of hydrogen. Monitor the progress of the reaction by thin-layer chromatography. Upon completion remove the catalyst by suction filtration through celite. Remove the solvent in vacuo to obtain the title compound.

1. customMonitor the progress of the reaction by thin-layer chromatography
2. customUpon completion remove the catalyst
3. filtrationby suction filtration through celite
4. customRemove the solvent in vacuo