Methanol → 4-Hydroxybenzaldehyde

HRID 1089598Notes

Reaction equation

HRID 1089598 reaction equation
CO.C[O:4][C:5]1[CH:12]=[CH:11][C:8]([CH:9]=[O:10])=[CH:7][CH:6]=1>O>[OH:4][C:5]1[CH:12]=[CH:11][C:8]([CH:9]=[O:10])=[CH:7][CH:6]=1

Participants

4

Reactant 2

HCID 887MethanolHCID 312444-Methoxybenzaldehyde

Product 1

HCID 1264-Hydroxybenzaldehyde

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

The reactions are carried out in a manner similar to Examples 1 to 19. However, water is added but no methanol. The starting material and reaction product and the blanketing stream of nitrogen are passed downward over the fixed-bed catalyst by the co-current method. With the aid of this downward-flow procedure, it is also possible to convert liquid phases. At 200° C., for example, the water will be in the form of steam but p-methoxybenzaldehyde (boiling point 248° C.) will still be substantially in the form of a liquid. In this case too, the desired p-hydroxybenzaldehyde is obtained.

Workup

  1. customThe starting material and reaction product
  2. customAt 200° C.

Sources & evidence

ORD record
ord-1bf930be29f44fc6971541e5f13391e8
Source dataset
uspto-grants-1990_10
Patent number
US04967013

Reaction notes

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