反应详情

A mixture of methyl 4-hydroxybenzoate (15.2 g, 0.1 M), 2-(benzenesulphonyloxy)ethyl chloride (28.65 g, 0.12 M) and potassium carbonate (19.15 g, 0.1 M) in 4-methylpentan-2-one (170 ml) was stirred at reflux for 24 hours. After cooling, distilled water (170 ml) was added and the organic phase separated off. Evaporation to dryness gave a yellow solid which was crystallised from ethanol to give the title compound, yield (13.3 g), m.p. 56°-58°.

1. temperatureat reflux for 24 hours
2. temperatureAfter cooling
3. distillationdistilled water (170 ml)
4. additionwas added
5. customthe organic phase separated off
6. customEvaporation to dryness
7. customgave a yellow solid which
8. customwas crystallised from ethanol