Ethanol → HCID 10272356, compound

HRID 1089752Notes

Reaction equation

HRID 1089752 reaction equation
[Cl:1][C:2]1[C:3]2[C:4]3[C:8](=[CH:9][CH:10]=1)[N:7]([CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:6](=S)[C:5]=3[CH:19]=[CH:20][CH:21]=2.[N:22]1([CH2:27][CH2:28][CH2:29][NH2:30])[CH:26]=[CH:25][N:24]=[CH:23]1.C(O)C>CN(C)C=O>[Cl:1][C:2]1[C:3]2[C:4]3[C:8](=[CH:9][CH:10]=1)[N:7]([CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:6](=[N:30][CH2:29][CH2:28][CH2:27][N:22]1[CH:26]=[CH:25][N:24]=[CH:23]1)[C:5]=3[CH:19]=[CH:20][CH:21]=2

Participants

5

Reactant 3

HCID 702EthanolHCID 787361H-Imidazole-1-propanamineHCID 15023426HCID 15023426, compound

Product 1

HCID 10272356HCID 10272356, compoundYield 64.8%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A mixture of 3.1 g of 6-chloro-1-(phenylmethyl)benz[cd]indole-2(1H)-thione (Cr), 1.4 g of 1H-imidazole-1-propanamine, 250 ml of ethanol, 75 ml of dimethylformamide, and 3.5 g of mercuric acetate is reacted as described in Example 3, giving 2.6 g of the desired product, mp 147°-149° C.

Workup

  1. customis reacted

Sources & evidence

ORD record
ord-7618a83fdbfb4e7c808723756a35e711
Source dataset
uspto-grants-1992_01
Patent number
US05079247

Reaction notes

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