Water → N-(6-amino-2,2-difluorocyclohexyl)-5-(difluoromethyl)-4-imidazo[1,2-b]pyridazin-3-ylthiophene-2-carboxamide
Reaction equation
[CH2:47]1[CH2:48][CH2:49][NH:50][CH2:51][CH2:52]1.[O:53]=[CH:54][N:55]([CH3:56])[CH3:57].[OH2:58].[cH:1]1[c:2]2[c:14]([cH:16][cH:17][cH:18]1)-[c:9]1[c:8]([cH:13][cH:12][cH:11][cH:10]1)[CH:3]2[CH2:4][N:15]([C:5](=[O:6])[O-:7])[CH:19]1[CH:20]([NH:27][C:28](=[O:29])[c:30]2[s:31][c:32]([CH:44]([F:45])[F:46])[c:33](-[c:35]3[cH:36][n:37][c:38]4[n:39]3[n:40][cH:41][cH:42][cH:43]4)[cH:34]2)[C:21]([F:25])([F:26])[CH2:22][CH2:23][CH2:24]1>>[NH2:15][CH:19]1[CH:20]([NH:27][C:28](=[O:29])[c:30]2[s:31][c:32]([CH:44]([F:45])[F:46])[c:33](-[c:35]3[cH:36][n:37][c:38]4[n:39]3[n:40][cH:41][cH:42][cH:43]4)[cH:34]2)[C:21]([F:25])([F:26])[CH2:22][CH2:23][CH2:24]1Participants
5
Sources & evidence
- ORD record
- ord-a8ca895d5d11454295bfce7211d9e933
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…