Hydrochloric Acid → 62922-45-6

Temperature

130 °C

1,500 parts of hydrochloric acid (chemically pure) are added to 137.5 parts of tetrahydrofurfurylamine hydrochloride at room temperature. The reaction solution is then heated to 130° C. in a pressure apparatus. This raises the pressure up to 8 bar. After a reaction time of 24 hours, the mixture is cooled to a temperature of 25° C. The dark brown solution is treated with activated carbon and filtered until it is clear, and the mother liquor is concentrated in a rotary evaporator. Recrystallization from 1,200 parts of ethanol gives 130 parts of an analytically pure product, 2,5-dichloropentylamine hydrochloride, having the following formula ##STR35##

1. temperatureThis raises the pressure up to 8 bar
2. temperatureAfter a reaction time of 24 hours, the mixture is cooled to a temperature of 25° C
3. additionThe dark brown solution is treated with activated carbon
4. filtrationfiltered until it
5. concentrationthe mother liquor is concentrated in a rotary evaporator
6. customRecrystallization from 1,200 parts of ethanol

ORD record

ord-5b51819644bf4d3f8f4955f07531e99b

Source dataset

uspto-grants-1992_01

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US05081296