2-Nitrotoluene → HCID 67838982, compound
Reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH3:10])([O-:3])=[O:2].[CH3:11][N:12](C(N(C)C)COC)C>CN(C=O)C>[NH2:12][CH:11]=[CH:10][C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=1[N+:1]([O-:3])=[O:2]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 120 °C
Procedure
20.6 g of o-nitrotoluene of 24 g of bis-(dimethylamino) ethoxy methane in 50 ml of DMF were initially introduced into a distillation apparatus and the mixture was heated at 120° C. for 6 h to form the β-amino-2-nitrostyrene. The ethanol was then removed by briefly applying vacuum.
Sources & evidence
- ORD record
- ord-03a4744d91fe4862bd5ea2128ea773de
- Source dataset
- uspto-grants-1992_01
- Patent number
- US05082976
Reaction notes
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