Methane → 2-Amino-6-methylpyridin-3-ol

HRID 1091012Notes

Reaction equation

HRID 1091012 reaction equation
[N+:1]([C:4]1[C:9]([OH:10])=[CH:8][CH:7]=[C:6]([CH3:11])[N:5]=1)([O-])=O.C>CO>[NH2:1][C:4]1[C:9]([OH:10])=[CH:8][CH:7]=[C:6]([CH3:11])[N:5]=1

Participants

4

Reactant 2

HCID 297MethaneHCID 848016-Methyl-2-nitropyridin-3-ol

Product 1

HCID 885002-Amino-6-methylpyridin-3-ol

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

3.5 g of 2-nitro-3-hydroxy-6-methylpyridine in 50 ml of methanol are placed under hydrogen pressure in the presence of one gram of palladinized charcoal. The mixture is stirred and filtered. The methanol is evaporated.

Workup

  1. filtrationfiltered
  2. customThe methanol is evaporated

Sources & evidence

ORD record
ord-ebbd8bfece5b4b7a8c778409133d6494
Source dataset
uspto-grants-1992_01
Patent number
US05084456

Reaction notes

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