Ammonia → HCID 178423494, compound

HRID 1091030Notes

Reaction equation

HRID 1091030 reaction equation
[C:1]([NH:9][C:10]([NH:12][C:13]1[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][C:14]=1[C:15]([NH2:17])=[O:16])=S)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.N.OO>CO>[CH3:22][C:19]1[CH:18]=[C:14]2[C:13](=[CH:21][CH:20]=1)[NH:12][C:10]([NH:9][C:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)=[N:17][C:15]2=[O:16]

Participants

5

Reactant 3

HCID 222AmmoniaHCID 784Hydrogen PeroxideHCID 151355262-[[(Benzoylamino)thioxomethyl)amino]-5-methylbenzamide

Product 1

HCID 178423494HCID 178423494, compoundYield 22.4%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a stirred mixture of 6 g of the above benzamide, 100 ml of methanolic ammonia and 200 ml of methanol was added dropwise, in increments, 20 ml of 30% hydrogen peroxide. After stirring overnight, the solid was collected, partially dissolved in 500 ml of hot acetonitrile and filtered. The filtrate was chilled, giving 1.2 g of the desired product as white crystals, mp 240°-242° C.

Workup

  1. customthe solid was collected
  2. dissolutionpartially dissolved in 500 ml of hot acetonitrile
  3. filtrationfiltered
  4. temperatureThe filtrate was chilled

Sources & evidence

ORD record
ord-c542bc006b4445779e9a3dee954567a2
Source dataset
uspto-grants-1992_01
Patent number
US05084457

Reaction notes

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