Benzoyl isothiocyanate → HCID 15135530, compound

HRID 1091033Notes

Reaction equation

HRID 1091033 reaction equation
[NH2:1][C:2]1[CH:10]=[C:9]([O:11][CH3:12])[C:8]([O:13][CH3:14])=[CH:7][C:3]=1[C:4]([NH2:6])=[O:5].[C:15]([N:23]=[C:24]=[S:25])(=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>CCOCC>[C:15]([NH:23][C:24]([NH:1][C:2]1[CH:10]=[C:9]([O:11][CH3:12])[C:8]([O:13][CH3:14])=[CH:7][C:3]=1[C:4]([NH2:6])=[O:5])=[S:25])(=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

4

Reactant 2

HCID 68284Benzoyl isothiocyanateHCID 108672362-Amino-4,5-dimethoxybenzamide

Product 1

HCID 15135530HCID 15135530, compoundYield 96.3%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

To a stirred mixture of 4 g of 2-amino-4,5-dimethoxybenzamide and 200 ml of ether was added dropwise, a solution of 3.3 g of benzoyl isothiocyanate in 100 ml of ether over 15 minutes. After 24 hours the solid was collected, giving 7 g of 2-[[(benzoylamino)thioxomethyl]amino]-4,5-dimethoxybenzamide.

Workup

  1. additionwas added dropwise
  2. customAfter 24 hours the solid was collected

Sources & evidence

ORD record
ord-1c547167972a442aa219695a14a7c01f
Source dataset
uspto-grants-1992_01
Patent number
US05084457

Reaction notes

Loading…