Ammonia → HCID 15027496, compound

HRID 1091038Notes

Reaction equation

HRID 1091038 reaction equation
[CH3:1][C:2]1[CH:23]=[CH:22][CH:21]=[CH:20][C:3]=1[C:4]([NH:6][C:7]([NH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[C:16]([NH:18][CH3:19])=[O:17])=S)=[O:5].N.OO>CO>[CH3:19][N:18]1[C:16](=[O:17])[C:11]2[C:10](=[CH:15][CH:14]=[CH:13][CH:12]=2)[N:9]=[C:7]1[NH:6][C:4](=[O:5])[C:3]1[CH:20]=[CH:21][CH:22]=[CH:23][C:2]=1[CH3:1]

Participants

5

Reactant 3

HCID 222AmmoniaHCID 784Hydrogen PeroxideHCID 15135529HCID 15135529, compound

Product 1

HCID 15027496HCID 15027496, compoundYield 25.4%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a stirred mixture of 6.6 g of the above benzamide, 100 ml of methanolic ammonia and 100 ml methanol was added, in increments, 20 ml of 30% hydrogen peroxide. After stirring overnight, the solid was collected, partially dissolved in 500 ml of hot acetonitrile and filtered. The filtrate was chilled, giving 1.5 g of the desired product as white crystals, mp 185°-186° C.

Workup

  1. customthe solid was collected
  2. dissolutionpartially dissolved in 500 ml of hot acetonitrile
  3. filtrationfiltered
  4. temperatureThe filtrate was chilled

Sources & evidence

ORD record
ord-f7d2095a112b4e7a9f69aa430cea8244
Source dataset
uspto-grants-1992_01
Patent number
US05084457

Reaction notes

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