Hydrochloric Acid → 2-(2-Carboxyfuran-5-yl-methyl)-1-(4-fluorobenzyl)-5-methanesulfonylindole

HRID 109172Notes

Reaction equation

HRID 109172 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[o:7][c:8]([CH2:11][c:12]2[n:13]([CH2:25][c:26]3[cH:27][cH:28][c:29]([F:32])[cH:30][cH:31]3)[c:14]3[cH:15][cH:16][c:17]([S:21](=[O:22])(=[O:23])[CH3:24])[cH:18][c:19]3[cH:20]2)[cH:9][cH:10]1.[CH2:36]1[O:37][CH2:38][CH2:39][O:40][CH2:41]1.[ClH:35].[Li+:33].[OH-:34]>>[O:3]=[C:4]([OH:5])[c:6]1[o:7][c:8]([CH2:11][c:12]2[n:13]([CH2:25][c:26]3[cH:27][cH:28][c:29]([F:32])[cH:30][cH:31]3)[c:14]3[cH:15][cH:16][c:17]([S:21](=[O:22])(=[O:23])[CH3:24])[cH:18][c:19]3[cH:20]2)[cH:9][cH:10]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 961HydroxideHCID 28486Lithium ionHCID 312751,4-DioxaneHCID 225044152-(2-Ethoxycarbonylfuran-5-yl-methyl)-1-(4-fluorobenzyl)-5-methanesulfonylindole

Product 1

HCID 225044032-(2-Carboxyfuran-5-yl-methyl)-1-(4-fluorobenzyl)-5-methanesulfonylindole

Sources & evidence

ORD record
ord-15bfb69e2e504bd2bc11b39f34c8bd12
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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