Lawesson's reagent → HCID 72581644, compound

HRID 1093941Notes

Reaction equation

HRID 1093941 reaction equation
[Si:1]([O:8][C:9]1[CH:18]=[C:17]([CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[CH:16]=[C:15]2[C:10]=1[C@@H:11]1[CH2:28][CH2:27][CH2:26][CH2:25][C@H:12]1[C:13](=O)[O:14]2)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].COC1C=CC(P2(SP(C3C=CC(OC)=CC=3)(=S)S2)=[S:38])=CC=1>C1(C)C(C)=CC=CC=1>[Si:1]([O:8][C:9]1[CH:18]=[C:17]([CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[CH:16]=[C:15]2[C:10]=1[CH:11]1[CH2:28][CH2:27][CH2:26][CH2:25][CH:12]1[C:13](=[S:38])[O:14]2)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 87949Lawesson's reagentHCID 69152767HCID 69152767, compound

Product 1

HCID 72581644HCID 72581644, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

2.00 g (4.97 mmol) of (6aR*,10aR*)-1-(tert-butyldimethylsilyloxy)-3-pentyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-6-one was heated under reflux at 140° C. for 17 h with 4.25 g (10.2 mmol) of Lawesson's reagent in xylene.

Sources & evidence

ORD record
ord-06c5c7974da642a6a2119e7650901676
Source dataset
uspto-grants-2012_03
Patent number
US08133887B2

Reaction notes

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