Malononitrile → HCID 86642079, compound

HRID 1094051Notes

Reaction equation

HRID 1094051 reaction equation
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([O:12][CH2:13][CH3:14])[CH:11]=1)[CH:7]=O)[CH3:2].[C:15](#[N:19])[CH2:16][C:17]#[N:18]>C(O)CC.[OH-].[K+]>[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([CH:9]=[C:10]([O:12][CH2:13][CH3:14])[CH:11]=1)[CH:7]=[C:16]([C:15]#[N:19])[C:17]#[N:18])[CH3:2]

Participants

5

Reactant 2

HCID 8010MalononitrileHCID 226086163,5-Diethoxybenzaldehyde

Product 1

HCID 86642079HCID 86642079, compound

Reagents, catalysts & solvents 2

HCID 14797Potassium HydroxideCatalystHCID 10311-PropanolSolvent

Procedure

To an amount of 56c (1.0 g, 5.15 mmole) of 3,5-diethoxybenzaldehyde dissolved in 10 mL of propanol, was added malononitrile (375 mg, 5.67 mmole) and 2 drops of sat. KOH. The mixture was stirred at r.t. for 10 mins. Precipitates was filtered to yield 1.0 g of 2-(3,5-diethoxybenzylidene)malononitrile (56d). MS [m+H] calc'd for C14H14N2O2, 243.11; found 243.11.

Workup

  1. customPrecipitates
  2. filtrationwas filtered

Sources & evidence

ORD record
ord-a4498435ade1404f93a12089c8cc320f
Source dataset
uspto-grants-2012_03
Patent number
US08133898B2

Reaction notes

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