Water → HCID 21625915, compound

HRID 1094334Notes

Reaction equation

HRID 1094334 reaction equation
[CH:1]([NH2:4])([CH3:3])[CH3:2].[C:5]1(=O)[CH2:10][CH2:9][CH2:8][C:7](=[O:11])[CH2:6]1.C1(C)C=CC(S(O)(=O)=O)=CC=1.O>C1C=CC=CC=1>[CH:1]([NH:4][C:5]1[CH2:10][CH2:9][CH2:8][C:7](=[O:11])[CH:6]=1)([CH3:3])[CH3:2]

Participants

6

Reactant 4

HCID 962WaterHCID 6101p-Toluenesulfonic acidHCID 6363IsopropylamineHCID 104341,3-Cyclohexanedione

Product 1

HCID 21625915HCID 21625915, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Equimolar amounts of isopropylamine and cyclohexane-1,3-dione were dissolved in benzene and heated with addition of p-toluenesulfonic acid to boiling with a water trap. After the trapping of water was complete, the mixture was thoroughly washed with water, the solvent was stripped off, and the residue was recrystallized.

Workup

  1. customto boiling with a water trap
  2. washthe mixture was thoroughly washed with water
  3. customthe residue was recrystallized

Sources & evidence

ORD record
ord-ac0f7555fe6f4429b5f50d42b7233143
Source dataset
uspto-grants-2012_03
Patent number
US08133913B2

Reaction notes

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