反应详情

In analogy to example 47 (step 2) and example 48 (steps 3 & 4), Quinolin-3-ylamine, (6-Trifluoromethyl-pyridin-3-yl)-acetonitrile & (S)-(+)-O-acetyl-L-mandelic acid were successively coupled and hydrolysed to give the target compound. MS(m/e): 452.1 [M+H]+.

1. customhydrolysed to give the target compound