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HRID1094409

反应详情

EQUATION

反应方程式

HRID 1094409 的结构方程式

REACTANTS

反应物

3
结构：Nc1ccc2c(c1)CCCC2
HCID75193

5,6,7,8-Tetrahydro-2-naphthylamine

C10H13N

结构：O=C(O)C(=O)c1ccc(F)cc1
HCID579440

未命名化合物

结构：N#CCc1ccc(C(F)(F)F)nc1
HCID50851127

未命名化合物

PRODUCTS

生成物

1
结构：O=C([C@@H](O)c1ccc(F)cc1)N(CCc1ccc(C(F)(F)F)nc1)c1ccc2c(c1)CCCC2
HCID44546438

未命名化合物

PROCEDURE

实验过程

In analogy to example 47 (steps 3 & 4), 5,6,7,8-Tetrahydro-naphthalen-2-ylamine, (6-Trifluoromethyl-pyridin-3-yl)-acetonitrile & (4-Fluoro-phenyl)-oxo-acetic acid were successively coupled then reduced to give after chiral chromatography (+ve rotation) the target compound. MS(m/e): 473.1 [M+H]+.

WORKUP

后处理

  1. customto give after chiral chromatography (+ve rotation) the target compound