HCID 57421777, compound → HCID 57421778, compound

HRID 1094928Notes

Reaction equation

HRID 1094928 reaction equation
C([O:5][C:6]([CH2:8][CH:9]([C:11]1[CH:20]=[CH:19][C:14]([C:15]([O:17][CH3:18])=[O:16])=[CH:13][CH:12]=1)[OH:10])=[O:7])(C)(C)C>FC(F)(F)C(O)=O>[C:6]([CH2:8][CH:9]([C:11]1[CH:20]=[CH:19][C:14]([C:15]([O:17][CH3:18])=[O:16])=[CH:13][CH:12]=1)[OH:10])([OH:7])=[O:5]

Participants

3

Reactant 1

HCID 57421777HCID 57421777, compound

Product 1

HCID 57421778HCID 57421778, compoundYield 100.8%

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

Methyl 4-(2-tert-butoxycarbonyl-1-hydroxyethyl)benzoate (140 mg, 0.50 mmol) was dissolved in trifluoroacetic acid (2.0 mL), and the resulting solution was left to stand at room temperature for 3 hours and concentrated to dryness under reduced pressure to give 113 mg of the desired product (stoichiometric yield).

Workup

  1. waitthe resulting solution was left
  2. concentrationconcentrated to dryness under reduced pressure

Sources & evidence

ORD record
ord-6fca4c6454be46d18bb85cd89104ab1b
Source dataset
uspto-grants-2012_03
Patent number
US08134013B2

Reaction notes

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