Hydrochloric Acid → 2-[4-(2,2,2-Trifluoro-1-hydroxy-ethyl)-phenyl]-2-aza-spiro[4.5]decane-1,8-dione
Reaction equation
[ClH:28].[F:1][C:2]([CH:3]([OH:4])[c:5]1[cH:6][cH:7][c:8]([N:11]2[C:12](=[O:25])[C:13]3([CH2:14][CH2:15][C:16]4([O:17][CH2:20][CH2:19][O:18]4)[CH2:21][CH2:22]3)[CH2:23][CH2:24]2)[cH:9][cH:10]1)([F:26])[F:27].[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1>>[F:1][C:2]([CH:3]([OH:4])[c:5]1[cH:6][cH:7][c:8]([N:11]2[C:12](=[O:25])[C:13]3([CH2:14][CH2:15][C:16](=[O:17])[CH2:21][CH2:22]3)[CH2:23][CH2:24]2)[cH:9][cH:10]1)([F:26])[F:27]Participants
4
Sources & evidence
- ORD record
- ord-94bfa859be544b4facaeae4bce15b639
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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