Hydrochloric Acid → HCID 66782075, compound

HRID 1095331Notes

Reaction equation

HRID 1095331 reaction equation
C(OC(=O)[NH:7][CH2:8][CH2:9][CH2:10][N:11]1[C:19]([O:20]C)=[N:18][C:17]2[C:12]1=[N:13][C:14]([O:23][CH2:24][CH2:25][CH2:26][CH3:27])=[N:15][C:16]=2[NH2:22])(C)(C)C.Cl>C(OCC)C.CCCC(C)C.O1CCOCC1>[NH2:22][C:16]1[N:15]=[C:14]([O:23][CH2:24][CH2:25][CH2:26][CH3:27])[N:13]=[C:12]2[C:17]=1[NH:18][C:19](=[O:20])[N:11]2[CH2:10][CH2:9][CH2:8][NH2:7]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 86628971HCID 86628971, compound

Product 1

HCID 66782075HCID 66782075, compound

Reagents, catalysts & solvents 2

HCID 312751,4-DioxaneSolventHCID 21882825Ether isohexaneSolvent

Procedure

The product from step (i) (1.1 g) was dissolved in methanol/DCM (1/1, 40 ml). 4N—HCl in dioxane (10 ml) was added and the mixture stirred at rt for 20 h. The resultant was concentrated under reduced pressure, which afforded the subtitle compound. Yield 0.9 g.

Workup

  1. concentrationThe resultant was concentrated under reduced pressure, which

Sources & evidence

ORD record
ord-68a4b9e0fbf94b55ab3cabb364b98ebb
Source dataset
uspto-grants-2012_03
Patent number
US08138172B2

Reaction notes

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