反应详情

(4-Oxo-2-phenyl-4,5-dihydro-2H-pyrazolo[3,4-c]quinolin-1-yl)acetic acid (8.83 g, 27.7 mmol) was suspended in 175 mL of chloroform. Twenty drops of DMF were added followed by oxalyl chloride (7.2 mL, 83.0 mmol). The reaction mixture was stirred at ambient temperature for 1 hour and concentrated under reduced pressure at 40° C. to afford crude (4-chloro-2-phenyl-2H-pyrazolo[3,4-c]quinolin-1-yl)acetyl chloride.

1. concentrationconcentrated under reduced pressure at 40° C.