反应详情

A solution of tryptamine (3.04 g, 19.0 mmol) and phthalic anhydride (3.0 g, 20.0 mmol) in toluene (300 ml) was boiled under reflux for 12 h using a water separator. The solvent was removed i. vac. and the residue was recrystallized from methylene chloride/cyclohexane. Yield: 4.46 g (81%)

1. temperatureunder reflux for 12 h
2. customThe solvent was removed i
3. customand the residue was recrystallized from methylene chloride/cyclohexane