反应详情

PdCl2(dppf) (14.8 g) was added to a CH3CN (900 mL) solution of methyl 4-bromo-3,5-dimethoxybenzoate (25.0 g), phenylboronic acid (22.2 g), Bu4NBr (5.86 g) and K3PO4 (77.2 g), and stirred under heat for 14 hours. This was filtered through Celite, and the filtrate was concentrated and purified through column chromatography to obtain the title compound as a colorless solid.

1. temperatureunder heat for 14 hours
2. filtrationThis was filtered through Celite
3. concentrationthe filtrate was concentrated
4. custompurified through column chromatography