Tetrahydrofuran → 4-(2-Fluoro-4-{[1-(4-fluorophenylcarbamoyl)cyclopropanecarbonyl]amino}phenoxy)pyridine-2-carboxamide
Reaction equation
[CH3:17][CH2:18][N:19]([CH2:20][CH3:21])[CH2:22][CH3:23].[F:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9](=[O:10])[C:11]2([C:14](=[O:15])[OH:16])[CH2:12][CH2:13]2)[cH:6][cH:7]1.[NH2:28][c:29]1[cH:30][c:31]([F:45])[c:32]([O:33][c:34]2[cH:35][c:36]([C:40](=[O:41])[NH2:42])[n:37][cH:38][cH:39]2)[cH:43][cH:44]1.[O:46]1[CH2:47][CH2:48][CH2:49][CH2:50]1.[S:24]([Cl:25])([Cl:26])=[O:27]>>[F:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9](=[O:10])[C:11]2([C:14](=[O:16])[NH:28][c:29]3[cH:30][c:31]([F:45])[c:32]([O:33][c:34]4[cH:35][c:36]([C:40](=[O:41])[NH2:42])[n:37][cH:38][cH:39]4)[cH:43][cH:44]3)[CH2:12][CH2:13]2)[cH:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-197ec831129d44d2b8bf54746c3433aa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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